class 1 histocompatibility antigen

class 1 histocompatibility antigen
антиген гистосовместимости 1 класса

English-Russian small dictionary of medicine. . 2015.

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  • histocompatibility antigen — A set of plasmalemmal glycoproteins that are crucial for T cell recognition of antigens. Particularly the HLA system in humans and the H2 system in mice. There are two classes of histocompatibility antigens: (1) Class I; histocompatibility… …   Dictionary of molecular biology

  • Minor histocompatibility antigen — are receptors on the cell surface of donated organs that are known to give an immunological response in some organ transplants[1]. They cause problems of rejection less frequently than those of the major histocompatibility complex (MHC). Minor… …   Wikipedia

  • major histocompatibility antigen — A set of plasmalemmal glycoprotein antigens involved in rapid (eg. 7 days in the mouse) graft rejection and other immune phenomena. The minor histocompatibility antigens are involved in much slower rejection phenomena. The major antigens show… …   Dictionary of molecular biology

  • Antigen — Each antibody binds to a specific antigen; an interaction similar to a lock and key. An antigen is a foreign molecule that, when introduced into the body, triggers the production of an antibody by the immune system. The immune system will then… …   Wikipedia

  • Antigen presentation — is a process in the body s immune system by which macrophages, dendritic cells and other cell types capture antigens and then enable their recognition by T cells. NOTOC The basis of adaptive immunity lies in the capacity of immune cells to… …   Wikipedia

  • Antigen processing — is a biological process that prepares antigens for presentation to special cells of the immune system called T lymphocytes. This process involves two distinct pathways for processing of antigens from an organism s own (self) proteins or… …   Wikipedia

  • Antigen-presenting cell — An antigen presenting cell (APC) or accessory cell is a cell that displays foreign antigen complexed with MHC on its surface. T cells may recognize this complex using their T cell receptor (TCR). Types APCs fall into two categories: professional… …   Wikipedia

  • antigen — Any substance that, as a result of coming in contact with appropriate cells, induces a state of sensitivity and/or immune responsiveness after a latent period (days to weeks) and that reacts in a demonstrable way with antibodies and/or immune… …   Medical dictionary

  • antigen presenting cell — A cell that carries on its surface antigen bound to MCH Class I or Class II molecules, and presents the antigen in this context to T cells. Includes macrophages, endothelium, dendritic cells and Langerhans cells of the skin. See also MHC… …   Dictionary of molecular biology

  • class II antigens — major histocompatibility antigens found only on immunocompetent cells, primarily B lymphocytes and macrophages; they are found on molecules consisting of two noncovalently bound chains, the 34,000 dalton α chain and 29,000 dalton β… …   Medical dictionary

  • Major histocompatibility complex — The major histocompatibility complex (MHC) is a large genomic region or gene family found in most vertebrates that encodes MHC molecules. MHC molecules play an important role in the immune system and autoimmunity. Proteins are continually… …   Wikipedia


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